- What is Graham’s disease?
- What causes Gorham’s disease?
- Which part of the body is affected by Gorham’s disease?
- What is vanishing bone disease?
- What does Paget’s disease look like?
- What are some examples of bone disease?
- What causes bone to disappear?
- What does osteomalacia feel like?
- Can your bones disappear?
- What does Paget’s disease of the bone look like?
- Can bone infections be cured?
- What would happen if your bones disappeared?
- How long does it take for Paget’s disease to progress?
- What is the most common age for females to be diagnosed with Paget’s disease?
- What is the rarest bone disease?
- What is the weirdest disease in the world?
- Can osteolysis be reversed?
- Is Paget’s disease an autoimmune disorder?
- What is Paget’s disease of the skull?
- What is the survival rate for Paget disease?
- What are the stages of Paget disease?
What is Graham’s disease?
Graham-Little-Piccardi-Lassueur syndrome (GLPLS) is a rare type of scarring hair loss.
It is most commonly found in otherwise healthy women between the ages of 30 and 70 years..
What causes Gorham’s disease?
The cause of Gorham-Stout is unknown. There is no evidence that the disease is hereditary or caused by environmental factors. However, active research is underway at Boston Children’s and other institutions to possibly identify a mutation that could cause the lymphatic and bone disorder.
Which part of the body is affected by Gorham’s disease?
It may affect any part of the skeleton, but most commonly involves the skull, collarbone (clavicle), pelvis, ribs, spine, and/or jaw. Depending on the bones affected, various complications may occur. The cause of Gorham’s disease is currently unknown.
What is vanishing bone disease?
Vanishing bone disease (Gorham-Stout syndrome) is a rare entity of unknown etiology, characterized by destruction of osseous matrix and proliferation of vascular structures, resulting in destruction and absorption of bone.
What does Paget’s disease look like?
Paget’s disease of the nipple always starts in the nipple and may extend to the areola. It appears as a red, scaly rash on the skin of the nipple and areola. The affected skin is often sore and inflamed, and it can be itchy or cause a burning sensation. The nipple can sometimes be ulcerated.
What are some examples of bone disease?
Related Health TopicsBone Cancer.Bone Density.Bone Infections.Osteogenesis Imperfecta.Osteonecrosis.Osteoporosis.Paget’s Disease of Bone.Rickets.
What causes bone to disappear?
Gorham’s disease (pronounced GOR-amz), also known as Gorham vanishing bone disease and phantom bone disease, is a very rare skeletal condition of unknown cause, characterized by the uncontrolled proliferation of distended, thin-walled vascular or lymphatic channels within bone, which leads to resorption and replacement …
What does osteomalacia feel like?
Symptoms of osteomalacia Muscle spasms and/or cramps. Muscle weakness, particularly in the thighs and buttocks. Waddling gait and/or difficulty walking. Feeling of pins and needles, known as paresthesia, or numbness around the mouth or in the arms and legs, in cases of calcium deficiency.
Can your bones disappear?
Gorham-Stout disease (GSD), which is also known as vanishing bone disease, disappearing bone disease, massive osteolysis, and more than a half-dozen other terms in the medical literature, is a rare bone disorder characterized by progressive bone loss (osteolysis) and the overgrowth (proliferation) of lymphatic vessels.
What does Paget’s disease of the bone look like?
X-rays provide images of dense structures, such as bone. Paget’s disease can usually be diagnosed by looking at an x-ray. A bone affected by Paget’s usually appears larger and denser than a normal bone. It may also have a deformed shape.
Can bone infections be cured?
Advertisement. Although once considered incurable, osteomyelitis can now be successfully treated. Most people need surgery to remove areas of the bone that have died. After surgery, strong intravenous antibiotics are typically needed.
What would happen if your bones disappeared?
Like other cells in your body, the bone cells rely on blood to keep them alive. Blood brings them food and oxygen and takes away waste. If bones weren’t made of living cells, things like broken toes or arms would never mend.
How long does it take for Paget’s disease to progress?
As a result, diagnosis may be delayed, often up to six months or more. Most individuals with the condition eventually seek medical attention due to associated itching or burning sensations, soreness, or pain of the affected area.
What is the most common age for females to be diagnosed with Paget’s disease?
Paget’s disease of the breast occurs most often in women older than age 50. Most women with Paget’s disease of the breast have underlying ductal breast cancer, either in situ — meaning in its original place — or, less commonly, invasive breast cancer.
What is the rarest bone disease?
Osteogenesis imperfecta (OI) is a rare disease leading to hereditary bone fragility.
What is the weirdest disease in the world?
Water allergy. … Foreign accent syndrome. … Laughing Death. … Fibrodysplasia ossificans progressiva (FOP) … Alice in Wonderland syndrome. … Porphyria. … Pica. … Moebius syndrome. Moebius is extremely rare, genetic and characterized by complete facial paralysis.More items…•
Can osteolysis be reversed?
Periprosthetic osteolysis Most patients recover from joint replacement surgery with no complications. But occasionally, polyethylene or other materials in a joint implant can wear down. When this happens, debris can accumulate in the surrounding joint tissue.
Is Paget’s disease an autoimmune disorder?
Paget’s disease of bone is a chronic autoimmune inflammatory disease that leads to an increase in bone reabsorption. While depression is extensively described in Paget’s disease, affecting up to 50% of patients, the prevalence of manic episodes is unknown.
What is Paget’s disease of the skull?
Paget’s disease of bone interferes with your body’s normal recycling process, in which new bone tissue gradually replaces old bone tissue. Over time, the disease can cause affected bones to become fragile and misshapen. Paget’s disease of bone most commonly occurs in the pelvis, skull, spine and legs.
What is the survival rate for Paget disease?
The prognosis and survival rate for Paget’s disease with a palpable mass are generally about the same as for generic infiltrating ductal carcinoma with a five-year survival rate of about 40% and a 10-year survival rate of about 20%.
What are the stages of Paget disease?
The key histopathological features of Paget disease involve the bone architecture and includes the three phases of the disease: mixed, osteolytic, and osteosclerotic. These phases may occur at the same time or separately.